Following the online discussion that took place on the International Museum Day with the representatives of the museums of Corfu, the Museum Collections of the Ionian University, continuing the effort to map the current issues that concerned the cultural institutions during the period of the COVID-19 pandemic, invited representatives from the museums of Corfu, Kefalonia, Lefkada, Zakynthos, and Ithaca to present their experiences from the first days of the reopening of their institutions. They discussed the weaknesses and problems faced by "small" museums, the social role of museum organizations and the ways in which a cultural organization can remain alive under the conditions of the pandemic and respond to the needs of modern man.